Is Neotame (Sweetener 2000) Safe?




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"The doctor of the future will give no medicine, but will interest his patients in the care of the human frame, in diet and in the cause and prevention of disease."
- Thomas Edison

Cancer is a political problem more than it is a medical problem.

"Dr. Gross told Congress that aspartame violated the Delaney Amendment, which had forbid anything being put in food you knew would cause cancer, and this was because without a shadow of a doubt, aspartame can cause brain tumors."

"And if the FDA violates the law, who is left to protect the public?"

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Sugar feeds cancer


RTM: Merisant Co., MSD Capital, Dell Computer Corp., NutraSweet Co.,
JW Childs Assc.: aspartame-neotame toxicity 7.10.2 rmforall
Karl T. Sestak, Communications
The Merisant Company
10 South Riverside Plaza, Suite 850
Chicago, Illinois 60606
312.840.6000   fax 312.840.5146

July 10, 2002     Hello Karl T. Sestak,

I last called and emailed you on 10.18.00.

Since March, 2000, Merisant Company has been a world manufacturer of aspartame products, supplying over a third of the world market in over 100 countries.

On late Friday, July 5, the  FDA announced its approval of Neotame (Sweetener 2000), based on its review of  "over 113 studies in animals and humans". So, I promptly  checked PubMed, which had 5 listings, none of which were about animal or human toxicity or dispositions in the body, whereas for aspartame there are now 701 listings.

You may search among 11 million medical citations on PubMed for any topic or author, and for many studies get an abstract summary:  .

It is remarkable to me that searches on Google or AllTheWeb reveal no published studies about neotame safety, although Sweetener 2000 is mentioned since 1987.  Common sense would appraise that if neotame was soundly safe, the industry would rush to publicize the research.  After all, the world sweetener market is fiercely competitive, with billion dollar stakes.  It is also notable that few, if any, neotame products are in Australia and New Zealand since the ANZFA approval there last

I am already contacting groups like Food Intolerance Network of Australia, whose Net newsletter has 955 members, to ask if those who are sensitive to a variety of chemicals, including aspartame, are reporting problems with any neotame products:  .

Can a corporation safely survive in this era of publicly disseminated information, save by only selling absolutely safe substances? Wouldn't any strategy of "information management", the longer and more apparently successful it seems to operate,
inevitably result in an even more catastrophic denounment, just as in the recent collapses of Enron and WorldCom?

Obviously, health and safety issues, for the common good, must be thoroughly aired in public arenas. The Net makes this inevitable.

If you provide a list of the 113 studies, abstracts and  full texts, many will review them carefully, and be very happy to give them the public approval they surely deserve. This would be the most expeditious way to launch a truly safe substance. Put every word of
every study on a public website, along with a permanent uncensored, public, archived email forum. Or, as in the case of aspartame, equivalent sites will emerge from the dire need of the people:  .,2163,100515,00.html
estimated 2001 revenues over $ 500 million, 700 employees

"With its nearly 20 brands, Merisant has more than just an Equal share of the tabletop sweetener market. Fueled  by Equal and its other flagship brand, Canderel, Merisant controls more than one-third of the market. Its aspartame-based products are sold in more than 100 countries; customers outside the US account for more than half of its
sales. Merisant was formed in 2000 when a group of investors (including Pegasus Capital Advisors, MSD Capital, and Brener International) bought the tabletop sweetener operations of biotech firm Monsanto. (Monsanto's NutraSweet-brand aspartame business -- a supplier to Merisant -- was sold to J.W. Childs Equity Partners.) A Searle scientist discovered aspartame in 1965; Canderel debuted in 1979.",2163,58863,00.html
MSD Capital LP    50 staff in 2001
645 Fifth Avenue, 21st Floor
NY, NY 10022-5910
212-303-1650  fax 212-303-1620

"Poor, poor Michael Dell: too much money and nowhere to put it. That's where MSD Capital comes in. Taking its name from Dell's initials, the investment firm handles the Dell Computer founder's personal investments in companies outside his namesake business, allowing him to focus on making PCs. Dell bankrolled MSD with approximately $1 billion in seed money in 1998 with the mandate to invest in promising technology startups and other companies; it has backed online bridal service, among others. In addition to VC investing, MSD Capital invests in public stocks and private equity deals, including LBOs and MBOs. The firm will occasionally invest in other investment firms' limited partnership funds."

Dell Computer Corporation
512-728-4100 Media Relations Team,2163,101064,00.html
The NutraSweet Company
10 S. Wacker Dr., Ste. 3200  Chicago, IL 60606 USA
Phone: +1 312-873-5000       Fax: +1 312-873-5050

$ 260 million revenues in 2000
375 employees in 2001,  + 7.1% growth in a year.

Chairman  Tim Healy
President and CEO  Nick E. Rosa [former Monsanto Senior Vice President]
CFO  William Schumacher

Investment firm J.W. Childs bought NutraSweet from Monsanto in 2000;
NutraSweet management also has a stake in the company.
J. W. Childs Associates, L.P.
111 Huntington Avenue - Suite 2900
Boston, MA 02199-7610
617-753-1100  617-753-1101

Rich Murray, MA    Room For All
1943 Otowi Road, Santa Fe  NM  USA  87505   505-986-9103  for 841 posts  45K post  30K post
RTM: NutraSweet Co.: Neotame toxicity questions 7.9.2 rmforall
RTM: Tholen: Diet Coke has 5 ppm formaldehyde from aspartame 5.29.2 rmforall
For 6 cans of diet soda, this is 5 times the daily limit of 1 PPM  for formaldehyde in drinking water, set by the EPA and the California Dept. of Health Services, Div. Drinking Water and Environmental Management   (916) 323-2308
Drinking Water Action Levels:   Contaminants of Current Interest
Last Update: May 2, 2002  5-page review
"Aspartame (NutraSweet) Addiction"
H.J. Roberts in "Townsend Letter", Jan 2000
Sunshine Sentinel Press  P.O.Box 17799  West Palm Beach, FL 33416
800-814-9800 561-588-7628 561-547-8008 fax
1038-page medical text   "Aspartame Disease: An Ignored Epidemic"
published May 30  2001    $ 85.00 postpaid    data from 1200 cases
available at
over 600 references from standard medical research    34 chapters
RTM: Moseley:
review Roberts "Aspartame Disease: An Ignored Epidemic" 2.7.2  rmforall
Ann Pharmacother 2001 Jun;35(6):702-6
Relief of fibromyalgia symptoms following discontinuation of dietary excitotoxins.
Smith JD, Terpening CM, Schmidt SO, Gums JG.
Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA.
RTM: Smith, Terpening, Schmidt, Gums:
full text: aspartame, MSG, fibromyalgia 1.17.2 rmforall
RTM: Hetle & Eltervaag: 2001 thesis
abstract: aspartame brain damage in mice:
Sonnewald 1995 study full text 2.17.2 rmforall
Headache 2001 Oct;41(9):899-901
Migraine MLT-Down: An Unusual Presentation of Migraine
in Patients With Aspartame-Triggered Headaches.
[Merck 10-mg Maxalt-MLT, for migraine, has 4 mg aspartame,
while 12 oz diet soda has 200 mg.]
Newman LC, Lipton RB.
Headache Institute, St. Lukes-Roosevelt Hospital Center, New York
NY Department of Neurology
Albert Einstein College of Medicine, Bronx, NY
Innovative Medical Research
WebMD: Barclay: Barth:
survey shows aspartame hurts memory in students 11.9.00
Timothy M. Barth Department of Psychology
Texas Christian University TCU Box 298920 Fort Worth, TX 76129
Chairman, Physiological Psychology   817-921-7410
Magnes Res 2001 Sep;14(3):189-94
The effect of oral aspartame administration on the
balance of magnesium in the rat.
Kovatsi L, Tsouggas M.
Laboratory of Forensic Medicine & Toxicology, Faculty of Medicine
Aristotle University of Thessaloniki, Greece
Measurement of molecular interaction of aspartame and
its metabolites with DNA. Clin Biochem. 1998 Jul;31(5):405-7.
Karikas GA, Schulpis KH, Reclos GJ, Kokotos G.
Dept. of Chemistry, University of Athens, Greece
Life Sci June 26 1998; 63(5): 337-49
Formaldehyde derived from dietary aspartame binds to tissue
components in vivo.   ["Trok-ho"]
Trocho C, Pardo R, Rafecas I, Virgili J, Remesar X,
Fernandez-Lopez JA, Alemany M, Departament de Bioquimica i
Biologia Molecular, Facultat de Biologia, Universitat de Barcelona,
Maria Alemany, PhD

Two teams find hot aspartame releases DKP, a potent carcinogen:
Food Addit Contam 2000 Oct; 17(10): 821-7
Simultaneous formation and detection of the reaction product of
solid-state aspartame sweetener by FT-IR/DSC microscopic system.
Lin SY, Cheng YD
Biopharmaceutics Laboratory,
Department of Medical Research & Education
Veterans General Hospital-Taipei, Shih-Pai, Taiwan,
Republic of China.
J Pharm Sci 1998 Apr; 87(4): 508-13
Hydration and dehydration behavior of aspartame hemihydrate.
Leung SS, Padden BE, Munson EJ, Grant DJ
Department of Pharmaceutics, College of Pharmacy,
University of Minnesota, Minneapolis 55455-0343, USA.
Sophie S. Leung, PhD
Dolores J. Grant, PhD
Lennart Hardell, M.D., PhD, in 1999 reported in Sweden that both
cell phone use and heavy aspartame use correlate with increased
brain cancers   +46 19 602 15 46
Russell L. Blaylock, M.D.   601-982-1175
"Excitotoxins, Neurodegeneration and Neurodevelopment"
The Medical Sentinel Journal Fall, 1999 , (95 references)
Journal Of The Diabetic Association Of  India
1995  Vol. 35, No. 4.  Emerging Facts About Aspartame
Dr. J. Barua (ophthalmic surgeon), Dr. Arun  Bal (surgeon)
(79 references)
"...the total amount of methanol absorbed will be approximately 10% of aspartame ingested. An EPA assessment of methanol states that methanol "is considered a cumulative poison due to the low rate of excretion once it is absorbed."  The absorbed methanol is then slowly converted to formaldehyde..."
"Reaction of formaldehyde with DNA has been observed,
by spectrophotometry and electron microscopy, to result in
irreversible denaturation."
"DKP has been implicated in the occurence of brain tumors."
Rich Murray: Professional House Doctors: Singer:  EPA: CPSC:
formaldehyde toxicity 6.10.1 rmforall
Rich Murray: 18 recent formaldehyde toxicity [Comet assay] abstracts
6.25.1 rmforall
Rich Murray: Gold: Koehler: Walton: Van Den Eeden: Leon:
aspartame toxicity 6.4.1 rmforall
Rich Murray: Simmons: Gold: Schiffman: Spiers:
aspartame toxicity 6.4.1 rmforal

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