Whole Body Hyperthermia and Mammary Tumours In Mice
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Inhibition by whole body hyperthermia with far-infrared rays of the growth of spontaneous mammary tumours in mice.
Udagawa Y, Nagasawa H, Kiyokawa S.
Anticancer Res. 1999 Sep-Oct; 19(5B):4125-30.
Experimental Animal Research Laboratory, Meiji University, Kawasaki, Japan.
To evaluate possible therapeutic benefits of irradiation with far-infrared rays (FIR) on breast cancer, we examined combined effects of the chronic exposure to FIR at ambient temperature (26.5-27.5 degrees C) and the whole-body hyperthermia (WBH) induced by FIR (WBH) (35-41 degrees C) on the growth of spontaneous mammary tumours of mice. A high mammary tumour strain of SHN virgin mice born on the normal rack or FIR rack were maintained on the respective racks until mammary tumour appearance. When the mammary tumour size reached approximately 7 mm, some mice in each group received no further treatment (Control and FIR groups, respectively) and the remaining mice received 3 hours of WBH each of 5 consecutive days (C + WBH and FIR + WBH groups, respectively). There was little difference between the control and FIR groups in the tumour growth over 10 days of examination. On the other hand, the tumour growth was inhibited significantly in both C + WBH and FIR + WBH groups and the degree of inhibition was similar. The data confirmed that the chronic exposure to FIR at ambient temperature has little effect on the growth of spontaneous mammary tumours in mice. WBH with FIR, however, strongly inhibited the tumour growth without deleterious side-effects, while chronic FIR irradiation itself again had little effect in this process. This WBH regimen may serve as a useful animal model for long-term studies of a noninvasive treatment of breast cancer.
Effects of far-infrared ray on reproduction, growth, behaviour and some physiological parameters in mice.
Udagawa Y, Nagawawa H.
In Vivo, 2000 Mar-Apr;14(2):321-6.
Experimental Animal Research Laboratory, Meigi University, Kanagawa, Japan.
The effects of chronic exposure to far-infrared ray (FIR) on reproduction, growth, behaviour, survival time and some related parameters were examined in SHN mice. The reproductive parameters differed slightly between the females on the normal racks and those on the FIR racks, which emitted FIR from the ceiling. The age and body weight on the day of vaginal opening was lower in the experimental mice born and maintained on the FIR rack than in the control on the normal rack. In both sexes, the levels of urinary components in the experimental group was significantly higher than the control at 6-7 months of age. Spontaneous motor activity of females during the light and dark phases were higher and lower, respectively, in the experimental group than the control. The survival rate was significantly higher in the experimental group than the control. These findings suggest that FIR has "normalization" effects' on the organisms.
"You cannot give breast cancer to rats that have sufficient iodine." - David Brownstein MD
Breast cancer in women and prostate cancer in men may be partly due to iodine deficiency.
Japanese women consume 25 times more dietary iodine than North American women and have much lower breast cancer rates. This dietary iodine comes from consumption of seaweed and other seafoods.
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